8 Quintillion Mutations: The Math That Breaks Creationist Claims
Dr. Joel Duff | 22 Nov. 2025
https://www.youtube.com/watch?v=UO6ObhGnJVk
1:07 Can you document 1 quadrillion mutations happened*, or is that what you conclude from supposing we developed from one-cellulars?
I can mention one post on Quora c. 10 years ago, or more, where someone used blind cichlids to prove evolution.
I looked it up thoroughly.
The retina depends, for correct development, on 10 genes. Two of these are mutated and the retina never develops, and this doesn't matter, since they live in the dark. When related species are cross-bred with them, that do not have the mutations, even one item of the correct version sufficed to make offspring with correct sight, correct retinas.
Now, each gene presumably had hundreds of loci, of triplets, and this poses the question: how many useless genes must an organism carry, until mutations make them useful?
- Fulminato
- @ilFulminat0
- gene imply you can transcribe in a protein. most of the human dna is not even functional, mean you cannot transcribe it. so...
- Hans-Georg Lundahl
- @hglundahl
- @ilFulminat0 OK, technicality, let me reformulate.
How many intranscribable DNA must an organism carry, before part of it by mutation becomes usefully transscribable, without interfering with non-transscribe functions of DNA, like timing of transscription?
4:01 By the way, thank you for mentioning 2 000 000 000 infections!
63.5 mill, 69.7 mill, 62.3 mill, 61.7 mill, 62.4 mill
319.6 mill died 2020 through 2024,
all causes ... how many of those are Covid?
There have been reported 7,101,788 (updated 15 October 2025) confirmed COVID-induced deaths worldwide.
Read that methodology is inverse between Covid infection and Covid vaccines. If an 80 year old diabetic has Covid when he dies, it's a Covid death. If an 80 year old diabetic got vaccinated and died, he died because 80 with diabetes. But let's say the numbers are something, not totally off.
7 101 788 / 319 600 000 = 2.222 % of deaths (or less, since the 7 101 788 is up to 15 Oct. 2025, the 319 600 000 only up to 31 Dec. 2024)
7 101 788 / 2 000 000 000 = 0.355 % die
Seems ... some over hysteria?
10:54 Hidden assumption: you change an actual parallellism of mutations into a serialism of them. No strand has 8 quintillion mutations. Given each infection is a new strand and several ones within it, I'll go back and see what your numbers were again ...
2 billion * 100 billion, let's assume that's like a triangular number in relation to the strands ... not sure if it's the best modelling, but here goes:
A simplified method for triangular roots = sqrt(2x), so 20 000 000 000
8 000 000 000 000 000 000 / 20 000 000 000 = 400 000 000 ... 400 million mutations per strand.
23:22 There is some lopsidedness to the (I suppose) implied parallel.
A virus is outsourcing all of its functioning, with very few exceptions, to host cells. That's why you can't cultivate them on petri dishes, unlike pathegens like bacteria or amoebae, and that's why vaccines involve artificially providing viruses with host cells (in the case of this virus, the host cell of choice has been a cell strand from an aborted boy in the 70's).
In that sense, a virus can afford lots more of "loss of function" because the losses hit what anyway isn't essential to it functioning.
30:39* I don't think that there is a model for mutations adding up to ten genes that are all needed for forming a retina.
- Trevor McKenna-Williams
- @MrDeadhead1952
- Guess no one at AIG drinks milk then.
- Jake Ramgren
- @JakeRamgren
- I understood this comment. 🔥🔥
- Hans-Georg Lundahl
- The mutation is in a way beneficial for the organism, but it still deletes information rather than produce it.
Going from A) info to turn on lactase production around birth and B) info to turn it off some years later to only A) isn't exactly like creating the info for lactase production and doesn't explain it.
- Trevor McKenna-Williams
- @hglundahl Actually I suggest you do some research before you post nonsense. No information has been deleted as the the allele that turns off production still exists and works but as the allele that turns it off is dominant Lactase is still produced.Lactase persistence is the result of at least six mutations (single-nucleotide polymorphisms – SNPs) have been associated with lactase expression.[25] They are all located in a region of the gene MCM6 upstream of LCT. This region is considered as an enhancer region for the transcription of LCT. This is a clear example of information not being lost. And this trait isn't sort of a benefit, it's a clear benefit as it allows an additional food source to be utilised for an entire life.
- Hans-Georg Lundahl
- @MrDeadhead1952 "the allele that turns off production still exists and works"
Oh? That is news to me. Well, enhancers would be another way for lactase production to get past that gene ... but they enhance, they still don't create new information.
Thank you for the info.
@MrDeadhead1952 By the way, on Trevor McKenna-Williams, a search, I don't find a scientist, but a resigned secretary and a business analyst ... are you sure you are also a good amateur at science?
* This is where he featured another video, which seemed to be about mutations adding up in us.
** In response to these words:
There's like one individual that has a has like just the right combination of 30:27 new changes that then go on to spread and then they have more mutations that find a few new 30:34 additions that are reach the sort of the magic threshold of making that virus 30:39 better for its current environment. Uh and so over time they add up sort of the the common mutations that they share 30:46 that are all functional mutations
